Preparation and physicochemical properties of uracil derivatives with potential biological activity
Pecorari, P.; Vampa, G.; Albasini, A.; Rinaldi, M.; Melegari, M.; Costi, M.P.
Il Farmaco; Edizione Scientifica 43(4): 311-318
1988
ISSN/ISBN: 0430-0920 PMID: 3203736 Document Number: 3281
The characterization of mono- and dimethylated 5-substituted uracils was re-examined. Analysis of their physicochemical properties (pKa, U.V., delta 1H-N.M.R.) affords insight into the structural characteristics of 5-substituted uracil alkylated at the ring nitrogens.
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