Effect of nicotine chewing gum on salivary secretion
Dunér-Engström, M.; Larsson, O.; Lundberg, J.; Fredholm, B.B.
Swedish Dental Journal 10(3): 93-96
1986
ISSN/ISBN: 0347-9994 PMID: 3460195 Document Number: 3263
The effect of nicotine, placebo for nicotine or menthol-tasting chewing gums on salivation was studied in 25 healthy volunteers. The chewing of a commercial nicotine containing (2 mg) chewing gum (Nicorette) did not give a larger rate of salivation than did the chewing of a placebo chewing gum. For both types of chewing gums the rate of salivation was highest during the initial 5 min and it decreased thereafter. Menthol-tasting chewing gum gave a significantly higher amount of stimulated saliva. It is concluded that the addition of nicotine to a chewing gum does not provide an additional stimulus for salivation.
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