Participation of the opioid-ergic system in the regulation of afferent reactions of the damaged myocardium
Bilibin, D.P.; Shevelev, O.A.; DzhaÄnendra UpadkhiaÄ
Biulleten' Eksperimental'noi Biologii i Meditsiny 106(10): 415-417
1988
ISSN/ISBN: 0365-9615 PMID: 2847827 Document Number: 324157
It has been established that in lesion of the myocardium accumulation of huge amount of algesic compounds may cause limitation of the level of cardiac afferentation. Use of naloxone, buterfanol tartrate and D-ala-2-lei-enkephalin prevent the development of the reaction. The possibility of participation of the endogenic cardiac opioids in anti-nociceptive reactions of heart during its lesion is considered.
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