Drug-induced hepatitis after dihydralazine treatment with fatal consequences
Machnik, G.; Bergert, A.; Justus, J.; Kunze, P.; Müller, R.; Reinhardt, M.; Schulz, H.; Stein, G.; Thiele, R.
Zentralblatt für Allgemeine Pathologie U. Pathologische Anatomie 134(2): 167-177
1988
ISSN/ISBN: 0044-4030 PMID: 3420978 Document Number: 319801
Adverse drug side effects of the antihypertensive substance dihydralazine have been increasingly observed in recent years. Damage is concentrated on the liver and is characterized by drug-induced hepatitis with confluent necrosis. Three cases (60 year old woman, 79 year old woman, 61 year old man) with lethal course after antihypertensive treatment, using dihydralazine are reported in this paper.