Drug induced fatal anaphylactic shock in Denmark 1968-1990
Lenler-Petersen, P.; Hansen, D.; Andersen, M.; Sørensen, H.T.; Bille, H.
Ugeskrift for Laeger 158(23): 3316-3318
1996
ISSN/ISBN: 0041-5782 PMID: 8686061 Document Number: 466615
Based on notifications to the Danish Committee on Adverse Drug Reactions and to the Central Death Register, 30 cases of fatal drug-induced anaphylactic shock were identified during the period 1968-1990. The most frequent causes were contrast media for X-ray examinations, antibiotics, and extracts of allergens. Nine cases occurred outside hospital; they were mainly caused by the use of allergen extracts of moulds for desensitization in general practice. Fatal drug-induced anaphylactic shock is rare, estimated in the present study at 0.3 cases per million inhabitants per year.