Lymphocytes in transplantation immunity--in the relation to HLA antigens
Takata, H.
Human Cell 1(3): 275-281
1988
ISSN/ISBN: 0914-7470 PMID: 2979204 Document Number: 316389
Allograft rejection, in kidney transplantation, is initiated by recipient's lymphocytes with the recognition of genetically determined antigens, histocompatibility antigens, which are expressed on the graft, followed by killer T cell induction and antibody production against the graft. Recent advances in our knowledge of the human major histcompatibility complex antigens-HLA antigens, which have an important role in transplantation immunity, are herein reviewed briefly and the relation to allograft rejection is discussed.