Top Abstract Purchase Related
Home
>
Node
>
Subnode

Mitogenic activity in ovine uterine fluids: characterization of a growth factor activity which specifically stimulates myoblast proliferation

Bird, R.C.; Bartol, F.F.; Daron, H.; Stringfellow, D.A.; Riddell, M.G.

Biochemical and Biophysical Research Communications 156(1): 108-115

1988

ISSN/ISBN: 0006-291X
PMID: 3178824
Document Number: 315002
Fluids produced by the uterus of pregnant sheep (OUF-ovine uterine fluids) were assayed for mitogenic activity in a thymidine incorporation assay. A dose-dependent mitogenic activity was observed in OUF which exceeded that of adult ovine plasma or fetal bovine serum. Uterine fluids were capable of stimulating thymidine incorporation in mouse 3T3 fibroblasts, rat L6 myoblasts, ovine trophoblast-derived cells, HeLa S3 cells, and bovine aortic endothelial cells. The greatest stimulation was observed in L6 myoblasts. The name ovine uterine-derived growth factor (ovine UDGF) has been suggested for this activity.

Document emailed within 1 workday
Secure & encrypted payments

Ihle, J.N.; Keller, J.; Oroszlan, S.; Henderson, L.E.; Copeland, T.D.; Fitch, F.; Prystowsky, M.B.; Goldwasser, E.; Schrader, J.W.; Palaszynski, E.; Dy, M.; Lebel, B. 1983: Biologic properties of homogeneous interleukin 3. I. Demonstration of WEHI-3 growth factor activity, mast cell growth factor activity, p cell-stimulating factor activity, colony-stimulating factor activity, and histamine-producing cell-stimulating factor activity Journal of Immunology 131(1): 282-287
Pim, D.; Collins, M.; Banks, L. 1992: Human papillomavirus type 16 E5 gene stimulates the transforming activity of the epidermal growth factor receptor Oncogene 7(1): 27-32
Seymour, L.W.; Shoaibi, M.A.; Martin, A.; Ahmed, A.; Elvin, P.; Kerr, D.J.; Wakelam, M.J. 1996: Vascular endothelial growth factor stimulates protein kinase C-dependent phospholipase D activity in endothelial cells Laboratory Investigation; a Journal of Technical Methods and Pathology 75(3): 427-437
Okamoto, M.; Nakamura, H.; Harada, N.; Shirasaka, T.; Fujii, S. 1984: Characterization of the activity of growth factor from AH-130 tumor cells Gan 75(2): 136-142
Xu, C.-J.; Wang, Y.-X.; Niu, B.-N.; Liu, B.; Li, Y.-B.; Wang, X.-M.; Lu, S.-L. 2014: Isolation and characterization of a novel lectin with mitogenic activity from Pleurotus ferulae Pakistan Journal of Pharmaceutical Sciences 27(4 Suppl): 983-989
Flossmann-Kast, B.B.; Jehle, P.M.; Hoeflich, A.; Adler, G.; Lutz, M.P. 1998: Src stimulates insulin-like growth factor I (IGF-I)-dependent cell proliferation by increasing IGF-I receptor number in human pancreatic carcinoma cells Cancer Research 58(16): 3551-3554
Bruce, C.B.; Pearson, C.K. 1983: A helix-destabilising protein from herpes simplex virus type I infected cells which specifically stimulates the virus induced DNA polymerase activity in vitro Biochemical and Biophysical Research Communications 116(1): 327-334
Cuadrado, A.; Carnero, A.; Dolfi, F.; Jiménez, B.; Lacal, J.C. 1993: Phosphorylcholine: a novel second messenger essential for mitogenic activity of growth factors Oncogene 8(11): 2959-2968
Ristimäki, A. 1989: Transforming growth factor alpha stimulates prostacyclin production by cultured human vascular endothelial cells more potently than epidermal growth factor Biochemical and Biophysical Research Communications 160(3): 1100-1105
Chandra, P.; Joel, D.D.; Chanana, A.D. 1983: Growth of ovine granulocyte-macrophage precursors in vitro without exogenous colony-stimulating activity American Journal of Veterinary Research 44(11): 2070-2072
Kuhara, A.; Tsuji, M.; Tsujimura, T.; Sugihara, A.; Yamada, N.; Terada, N. 1999: Comparison of sensitivities of uterine cells in their proliferation responding to epidermal growth factor and estrogen between neonatal and postneonatal mice In Vivo 13(6): 487-491
Lynch, M.J.; Pelosi, L.; Carboni, J.M.; Merwin, J.; Coleman, K.; Wang, R.C.; Lin, P.F.; Henry, D.L.; Brattain, M.G. 1993: Transforming growth factor-beta 1 induces transforming growth factor-alpha promoter activity and transforming growth factor-alpha secretion in the human colon adenocarcinoma cell line FET Cancer Research 53(17): 4041-4047
Singh, V.; Singh, R.C. 1999: Modification of ovine luteinizing hormone subunits with SMPT and its effect on subunit recombination, immunological activity, receptor binding and steroidogenic activity Indian Journal of Experimental Biology 37(9): 849-858
Zhang, C-hua.; Wen, Z-qing.; Li, J-feng.; Li, C-zhong.; Shi, M.; Yang, G-wen.; Lan, S-min.; Zhu, Y.; Wang, F.; Zhang, Y-jing.; Wang, Y-ying.; Zhang, H. 2008: Inhibition of proliferation and transforming growth factor beta3 protein expression by peroxisome proliferators-activated receptor gamma ligands in human uterine leiomyoma cells Chinese Medical Journal 121(2): 166-171
Vink, A.; Vandenabeele, P.; Uyttenhove, C.; Cayphas, S.; Van Snick, J. 1988: Plasmacytoma growth factor activity of murine granulocyte-macrophage colony-stimulating factor Journal of Immunology 141(6): 1996-1999
Andresen, J.L.; Ehlers, N. 1998: Chemotaxis of human keratocytes is increased by platelet-derived growth factor-BB, epidermal growth factor, transforming growth factor-alpha, acidic fibroblast growth factor, insulin-like growth factor-I, and transforming growth factor-beta Current Eye Research 17(1): 79-87
Zhang, B.; Huang, H-Zhang.; Tao, Q.; Liu, X-Qiang.; Wei, J. 2006: Association of matrix metalloproteinase-2 activity with cell proliferation and growth in ameloblastoma Hua Xi Kou Qiang Yi Xue Za Zhi 24(1): 7-10
Opperman, L.A.; Chhabra, A.; Cho, R.W.; Ogle, R.C. 1999: Cranial suture obliteration is induced by removal of transforming growth factor (TGF)-beta 3 activity and prevented by removal of TGF-beta 2 activity from fetal rat calvaria in vitro Journal of Craniofacial Genetics and Developmental Biology 19(3): 164-173
Steel, L.K.; Bach, D.; Kaliner, M.A. 1982: Prostaglandin-generating factor of anaphylaxis. II. Characterization of activity Journal of Immunology 129(3): 1233-1238
Louahed, J.; Renauld, J.C.; Demoulin, J.B.; Baughman, G.; Bourgeois, S.; Sugamura, K.; Van Snick, J. 1996: Differential activity of dexamethasone on IL-2-, IL-4-, or IL-9-induced proliferation of murine factor-dependent T cell lines Journal of Immunology 156(10): 3704-3710