Campylobacter pylori-associated chronic gastritis: a new entity in gastroduodenal diseases?
Börsch, G.; Wegener, M.
Leber Magen Darm 18(1): 9-16
1988
ISSN/ISBN: 0300-8622 PMID: 3280934 Document Number: 314491
Clinical, morphological and immunological data in addition to animal studies clearly support the conclusion, that Campylobacter pylori infection is a direct cause (sufficient condition) for chronic type B gastritic in man. C. pylori gastritis is primarily a histologic entity defined by the presence of a gastric mucosal cellular infiltrate and the histologic demonstration of typical curved bacilli. Preliminary findings indicate, that this infection is not associated with a specific combination of symptoms. Also, it is not exclusively confined to human beings, since this or similar infections appear to represent a rather common phenomenon of mammalian stomachs. The emergence of C. pylori gastritis as a distinct entity may give rise to a new classification of dyspeptic disorders based on etiologic considerations. However, the clinical impact of C. pylori will in all likelihood depend primarily on the as yet unestablished therapeutic potential to effectively eradicate the organisms.