Biochemical changes in acute noise stress in rats

Prabhakaran, K.; Suthanthirarajan, N.; Namasivayam, A.

Indian Journal of Physiology and Pharmacology 32(2): 100-104

1988


ISSN/ISBN: 0019-5499
PMID: 3182056
Document Number: 314146
The effects of acute auditory stress on certain biochemical parameters like blood corticosterone, total cholesterol, triglyceride, Serum glutamic pyruvic transaminase (SGPT) and Serum glutamic oxaloacetic transaminase (SGOT) were studied in albino rats. A significant increase was observed in the blood level of corticosterone, total cholesterol, SGOT and SGPT while a marked reduction was noticed in the Sr. triglyceride level. These data indicate that noise could be a potent stressor and cause distrubances in the biochemical parameters of the body. It is presumed that most of the effects are indirect, being manifested through the activation of autonomic nervous system which liberates catecholamines and hypothalamo pituitary adrenal axis responsbile for the liberation of corticosteroids.

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