Effect of alpha-tocopheryl acetate on blood biochemical parameters in albino rats as affected by acoustic stress
Melkonian, M.M.; Mkhitarian, V.G.
Biulleten' Eksperimental'noi Biologii i Meditsiny 100(9): 270-272
1985
ISSN/ISBN: 0365-9615 PMID: 4041586 Document Number: 258222
Experiments on random-bred white male rats have demonstrated the activation of induced lipid peroxidation in red cell membranes, elevation on the basal level of plasma lipid peroxides, a decrease in the content of alpha-tocopherol in plasma and red blood cell membranes, considerable shifts in the content of esterified and free cholesterol in plasma and red blood cell membranes under prolonged acoustic stress (91 dB). Administration of alpha-tocopheryl acetate in a dose of 1 mg/kg exerted a beneficial effect on the test parameters under prolonged acoustic stress.