Monoclonal antibodies against human leucocyte antigens. II. Antibodies against CD45 (T200) , CD3 (T3) , CD43, CD10 (CALLA) , transferrin receptor (T9) , a novel broadly expressed 18-kDa antigen (MEM-43) and a novel antigen of restricted expression (MEM-74)
Horejsí, V.; Angelisová, P.; Bazil, V.; Kristofová, H.; Stoyanov, S.; Stefanová, I.; Hausner, P.; Vosecký, M.; Hilgert, I.
Folia Biologica 34(1): 23-34
1988
ISSN/ISBN: 0015-5500 PMID: 2968928 Document Number: 313145
The specificities of several monoclonal antibodies described by us earlier were determined more exactly: (1) antibodies MEM-31 and MEM-32 are directed against CD8 and CD5 T cell antigens, respectively; (2) MEM-15 and MEM-18 react with the CD14 monocyte antigen; (3) MEM-28 recognizes the CD45 pan-leukocyte antigen. Several new monoclonal antibodies are described: (4) MEM-55 and MEM-58, reactive with subsets of CD45-related molecules; (5) MEM-43, recognizing a broadly expressed 18-kDa glycoprotein; (6) MEM-57, reacting with the CD3 antigen complex; (7) MEM-59 recognizing the CD43 leukocyte antigen; (8) MEM-74, which reacts with an unidentified antigen strongly expressed on several cell lines and many leukemic cells but absent from most resting leukocytes; (9) MEM-75, directed against transferrin receptor, and (10) MEM-78, recognizing CD10 (CALLA) antigen.