Nucleic acid analogs for high performance liquid chromatography

Inaki, Y.; Takemoto, K.

Nucleic Acids Symposium Series 19: 45-48

1988


ISSN/ISBN: 0261-3166
PMID: 3226921
Document Number: 312670
HPLC resins containing nucleic acid base derivatives were successfully prepared. These resins were found to give excellent complementary separation of nucleic acid base derivatives, nucleosides, nucleotides, and oligonucleotides. These resins may be useful for separation of components of nucleic acids and polynucleotides as a specific separation system, while ion-exchange and reverse-phase systems are non-specific separation systems.

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