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Experimental models for the study of chronoimmunomodulation (rhythms of the springtail Folsomia candida, Collembola: Isotomidae)

Marques, M.D.; Cornélissen, G.; Cutkomp, L.K.; Halberg, F.; Marques, N.

Chronobiologia 15(1-2): 183-189

1988

ISSN/ISBN: 0390-0037
PMID: 3416674
Document Number: 312462
A third-generation cephalosporine, cefodizime, was tested in two experiments on the springtail, Folsomia candida, used as a model of infradian rhythmicity. Any effect on ecdysis (molt), oviposition and oviproduction was sought for 6, 20 or 60 ng of cefodizime administered with brewer's yeast every other day, as compared to controls given only the yeast. Results indicate that a 20-ng dose of cefodizime on alternate days may shorten an infradian period (of molt) in the springtail.

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