The effect of immunosuppressors and low temperature on the activity of collagenase in the cornea
Toczolowski, J.
Annals of Ophthalmology 20(2): 64-67
1988
ISSN/ISBN: 0003-4886 PMID: 2833866 Document Number: 311869
In experimental studies, it has been shown that the administration of either cryotherapy or cystostatic immunosuppressors caused a decrease in the infiltration of inflammatory cells in alkali-burned corneas. The activity of collagenase was observed to be inhibited in such corneas, and they healed faster than controls. Low temperature inhibits the activity of collagenase by removing the infiltration of inflammatory cells, and this therapy can be considered favorable in many diseases of the cornea.