Morphocytochemical and electron microscopic research on murine hybridoma cells producing and not producing monoclonal antibodies

Sidorenko, S.P.; Gluzman, D.F.; Vetrova, E.P.; Iurchenko, O.V.; Berdova, A.G.; Sidorenko, S.P; Gluzman, D.F; Vetrova, E.P; Iurchenko, O.V; Berdova, A.G

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Morphocytochemical and electron microscopic research on murine hybridoma cells producing and not producing monoclonal antibodies

Sidorenko, S.P.; Gluzman, D.F.; Vetrova, E.P.; Iurchenko, O.V.; Berdova, A.G.

Tsitologiia 30(1): 39-43

1988

ISSN/ISBN: 0041-3771

PMID: 3358281

Document Number: 309719

Cytochemical and ultrastructural features of mouse hybridomas and also of the parental cells--myeloma P3-X63-Ag8.653 and spleen cells of the Balb/c mice immunized with cell line RPMI-1788 have been studied. Differences in cytomorphological signs and activity of acid phosphatase, acid nonspecific esterase, nonspecific-alpha-naphthyl acetate esterase were shown in hybrid cell lines secreting and not secreting monoclonal antibodies.