Effects of prostaglandin F2 alpha on degranulation of bovine luteal cells on days 4 and 12 of the estrous cycle
Braun, N.S.; Heath, E.; Chenault, J.R.; Shanks, R.D.; Hixon, J.E.
American Journal of Veterinary Research 49(4): 516-519
1988
ISSN/ISBN: 0002-9645 PMID: 3163904 Document Number: 305686
Corpora lutea were collected from 18 beef heifers on day 4 or 12 of the estrous cycle, 1 hour after prostaglandin (PG) F2 alpha or saline (control) treatment. Five heifers also were treated with PGF2 alpha on day 4, but their corpora lutea were not collected until day 12. The relative percentage of cytoplasm occupied by granules decreased only in large luteal cells (LLC) in heifers given PGF2 alpha on day 12, compared with the percentage in controls. Small luteal cells (SLC) were not as affected. The luteal concentration of progesterone was similarly decreased only in heifers given PGF2 alpha on day 12. Treatment of heifers with PGF2 alpha on day 4 had no marked effect on progesterone values or on the relative percentage of cytoplasm occupied by granules in LLC or SLC. Seemingly, LLC were more responsive to PGF2 alpha than were SLC, and PGF2 alpha treatment of beef heifers at day 4 did not markedly impair luteal function.