Calorimetry of chromatin and DNA from ascitic cells of C3HA mice in the presence of copper ions
Patiashvili, L.D.; Chanchalashvili, Z.I.; Chitadze, G.S.; Madzhagaladze, G.V.; Monaselidze, D.R.
Biofizika 32(2): 300-303
1987
ISSN/ISBN: 0006-3029 PMID: 3580399 Document Number: 299983
The process of chromatin denaturation in the composition of C3HA line mice ascites cells was investigated by the method of scanning microcalorimetry. It is shown that copper ions injected into ascites tumour are inculcated in DNA double helix and injure it, and this caused disorder of high ordered chromatin structure.
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