Top Abstract Purchase Related
Home
>
Node
>
Subnode

Effect of myelopeptides on the synthesis of DNA and total protein in the cells of the lymphoid organs in the mouse

Strelkov, L.A.; Stepanenko, R.N.; Mikhaĭlova, A.A.

Biulleten' Eksperimental'noi Biologii i Meditsiny 104(12): 703-706

1987

ISSN/ISBN: 0365-9615
PMID: 3689965
Document Number: 298593
Using double 3H-thymidine/14C-amino acid label, the influence of myelopeptides (MP) on chromosomal DNA and total protein (without histones) synthesis has been studied in vitro in mouse lymphoid organ cells. It has been shown that MP cause a decrease in DNA labelling and a parallel increase in protein labelling in bone marrow cells and have practically no effect on these two parameters in thymus, lymph node and spleen cells. It has been found that MP have only mitogenic effect on the above-mentioned organ cells, but in combination with 2-mercaptoethanol. The data obtained show that MP possess the properties of cell-differentiating factors.

Document emailed within 1 workday
Secure & encrypted payments

Gushchin, I.S.; Iamshchikova, O.A.; Prozorovskiĭ, N.S. 1991: Modulating effect of mast cells on the proliferation of cells from various lymphoid organs of rats Patologicheskaia Fiziologiia i Eksperimental'naia Terapiia 6: 31-33
Ogawa, H.; Tsunematsu, T. 1985: Therapeutic effect of total lymphoid irradiation in the SLE symptoms in the NZB/W F1 mouse Nihon Rinsho. Japanese Journal of Clinical Medicine 43(1): 180-184
Komolova, G.S. 1980: Effect of hypokinesia on nucleic acid and protein metabolism in the lymphoid organs of rats Biulleten' Eksperimental'noi Biologii i Meditsiny 90(11): 548-550
Adkins, B.; Gandour, D.; Strober, S.; Weissman, I. 1988: Total lymphoid irradiation leads to transient depletion of the mouse thymic medulla and persistent abnormalities among medullary stromal cells Journal of Immunology 140(10): 3373-3379
Görmar, F.E.; Bernd, A.; Holzmann, H. 1990: The effect of hydrocortisone aceponate on proliferation, total protein synthesis and collagen synthesis in human skin fibroblasts in vitro Arzneimittel-Forschung 40(2 Part 1): 192-196
Abakumova, O.I.; Kariakin, A.V.; Skvortsov, I.A.; Tsvetkova, T.A.; Iakusheva, I.V.; Vasil'ev, G.S.; Kondakova, L.I. 1998: Effects of cattle brain tissue hydrolysates on the protein synthesis in various organs of mice and cultured cells Biulleten' Eksperimental'noi Biologii i Meditsiny 126(8): 171-174
Blazer, B.A.; Heppner, G.H. 1978: In situ lymphoid cells of mouse mammary tumors. II. the characterization of lymphoid cells separated from mouse mammary tumors Journal of Immunology 120(6): 1881-1886
Petrova, I.I. 1970: Effect of 6-mercaptopurine on the intensity of protein synthesis in the blood and organs of rats with skin homografts Farmakologiia i Toksikologiia 33(5): 595-597
Krivokhizhina, L.V. 1991: The effect of the humoral action of the cells from chick embryo hematopoietic organs on the colony-forming capacity of normal mouse bone-marrow cells and in activated erythropoiesis Patologicheskaia Fiziologiia i Eksperimental'naia Terapiia 3: 38-40
Ozato, K. 1973: Long-term survival of mouse thymic lymphoid cells in vitro: effect of human serum Journal of Immunology 111(5): 1459-1469
Ghosh, S. 1975: Nucleic acids and protein synthesis in adenosine treated Ehrlich mouse ascites tumour cells Indian Journal of Experimental Biology 13(3): 290-292
Mykhaĭlyk, I.V.; Prokopova, K.V.; Ostapchenko, L.I.; Kucherenko, M.I. 2003: Activity of dsRNA-dependent protein kinase in rat lymphoid cells under the effect of X-ray irradiation Ukrains'kyi Biokhimichnyi Zhurnal 75(1): 49-53
Koterov, A.N. 1997: Effect of zinc-metallothionein on DNA replicative synthesis and single-stranded DNA-binding protein (SSB-protein) content in chromatin of mice bone marrow cells Ukrainskii Biokhimicheskii Zhurnal 69(1): 84-87
Vatin, A.E. 1980: Action of the antitumor antibiotics, rubomycin and carminomycin, on the T- and B-cell population ratio in mouse lymphoid organs Antibiotiki 25(11): 860-864
Teillaud, J.L.; Fourcade, A.; Huppert, J.; Fridman, W.H.; Tapiero, H. 1989: Effect of doxorubicin on mouse hybridoma B cells: stimulation of immunoglobulin synthesis and secretion Cancer Research 49(18): 5123-5129
Marcsek, Z.; Menyhárt, J. 1982: Partial purification from bovine pulmonary tissue of a protein capable of inhibiting in vivo DNA synthesis in mouse pulmonary cells Acta Physiologica Academiae Scientiarum Hungaricae 59(4): 349-358
Håkansson, L. 1975: Effect of cytostatic drugs on nucleic acid synthesis in mouse thymocytes and chick embryo cells Arzneimittel-Forschung 25(3): 378-382
Gel'shteĭn, V.I.; Stavrovskaia, A.A. 1972: Effect of colcemid on cell movement, mitosis and DNA synthesis in a culture of mouse embryonic fibroblast-like cells Biulleten' Eksperimental'noi Biologii i Meditsiny 73(6): 94-96
Cheema, I.R.; Hermann, C.; Postell, S.; Holifield, B. 1999: Effect of tumour necrosis factor-alpha on total myofibrillar and sarcoplasmic protein synthesis and polysomal aggregation in rat skeletal muscles Cytobios 97(386): 133-139
Fotiadis, C.; Sergiou, C.; Kyrou, I.; Troupis, T.G.; Tselentis, J.; Doussaitou, P.; Gorgoulis, V.G.; Sechas, M.N. 1999: Experimental echinococcus infection in the mouse model: pericystic cellular immunity reaction and effects on the lymphoid organs of immunocompetent and thymectomized mice In Vivo 13(6): 541-546