Fluid-loading test for determination of dehydration and hydration
Fukutomi, O.; Takaori, M.; Yano, H.; Yoshida, H.; Fukui, A.
Masui. Japanese Journal of Anesthesiology 36(9): 1407-1413
1987
ISSN/ISBN: 0021-4892 PMID: 3694780 Document Number: 294980
Thirty-six adult patients subjected to restriction of water intake for 12 hours prior to general anesthesia for surgery other than thoracotomy and craniotomy were divided into 3 groups. Group I consisted of 12 patients without body fluid adjustment after the induction of anesthesia. Group II consisted of 12 patients who received 15 ml/kg fluid supplementation over a 30 min period. Group III consisted of 12 patients who received 30 ml/kg fluid supplementation over a period of 60 min. No difference in CVP was noted between these groups. With 6 ml/kg fluid loading over a period of 5 minutes, the rise of CVP was 2.4 .+-. 1.3 in Group I, 2.0 .+-. 2.4 in Group II and 1.2 .+-. 0.8 cmH2O in Group III. The time required for the fall of the pressure to the preloading level was estimated to be 334 min in Group I, 17 in Group II and 10 in Group III, and the time required for 50% fall to be 85 min in Group I, 7 in Group II and 4 in Group III. Fluid loading of 6 mg/kg may be employed as a method to assess the degree of hydration or body fluid balance by observing for 5 .apprx. 10 minutes, without markedly influencing metabolic state of the organism.