Determination of protein in cerebrospinal fluid: comparison of the Coomassie-Blue method and the Cu-Folin differential test

Schnell, R.; Jegge, S.; Rieder, H.P.

Journal of Clinical Chemistry and Clinical Biochemistry 21(3): 151-155

1983


ISSN/ISBN: 0340-076X
PMID: 6854226
Document Number: 206580
Comparison of within-run and between-day imprecision of protein assays using CSF controls as well as 96 random CSF samples from the routine laboratory shows that the Cu-Folin differential test and the Coomassie-Brilliant-Blue method from Bio-Rad are equally suited to total protein determination in cerebrospinal fluid. Problems possibly arising with very low concentrations of CSF or urine protein and the influence of some drugs often used in the neurological clinic are presented and discussed.

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