Separation and identification of impurities in Chinese norgestrel
Fang, X.G.; Song, Y.W.
Yao Xue Xue Bao 22(9): 690-693
1987
ISSN/ISBN: 0513-4870 PMID: 3445761 Document Number: 294267
In this paper, the separation and identification of two impurities in Chinese norgestrel were reported. TLC and HPLC analysis indicated that Chinese norgestrel contains six impurities. On the basis of the RV, IR spectroscopy, EI mass spectrometry and comparison with reference substances, the two impurities were identified as ( .+-. ) 13 .beta.-ethyl-gon-4-ene-3,17-dione and (.+-.)13.beta.-ethyl-17.beta.-hydroxy-gon-4-ene-3-one.