Phase Ii treatment of central nervous system gliomas with high-dose etoposide and autologous bone marrow transplantation
Giannone, L.; Wolff, S.N.
Cancer Treatment Reports 71(7-8): 759-761
1987
ISSN/ISBN: 0361-5960 PMID: 3038317 Document Number: 292033
A total of 16 patients with progressive CNS gliomas who had previously received maximal radiation therapy and chemotherapy were treated on a phase II study using high-dose etoposide with autologous bone marrow transplantation to assure hematopoietic recovery. Three patients (19%) responded with both improved neurological status and decreased mass on computerized tomographic scan. Median survival for all treated patients was 4 months with the three responders living 9, 10, and 54+ months.
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