Nuclear matrix association regions of rat alpha 2-macroglobulin gene
Ito, T.; Sakaki, Y.
Biochemical and Biophysical Research Communications 149(2): 449-454
1987
ISSN/ISBN: 0006-291X PMID: 2447878 Document Number: 290312
We have identified DNA fragments which bind specifically to the nuclear matrix in vitro, termed matrix association regions (MARs), in the first and fourth introns of rat alpha 2-macroglobulin gene. The MAR in the first intron is enriched with sequences closely related to the cleavage consensus of topoisomerase II, and contains the binding site of nuclear factor-alpha, a sequence-specific DNA binding protein reported previously.
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