Enhancement of monomethylaminoantipyrine-induced increase of hepatic gamma-glutamyltranspeptidase activity by cobaltous chloride in rats
Hoshi, K.; Senda, N.; Igarashi, T.; Satoh, T.; Ueno, K.; Kitagawa, H.
Research Communications in Chemical Pathology and Pharmacology 51(1): 81-88
1986
ISSN/ISBN: 0034-5164 PMID: 2869556 Document Number: 286170
Co-administration of MAA and CoCl2 enhanced the MAA-induced increase of hepatic microsomal gamma-GTP activity in rats. This may be explained by a fact that inhibition of MAA metabolism in hepatic microsomes by CoCl2 led to increase plasma concentration of MAA which, in turn, induction of gamma-GTP by MAA was potentiated.
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