The action of hormones on the rat uterus and mammary gland gamma-glutamyltranspeptidase activity
Villanueva, S.; Puente, J.; Sapag-Hagar, M.
Research Communications in Chemical Pathology and Pharmacology 57(1): 99-105
1987
ISSN/ISBN: 0034-5164 PMID: 2890190 Document Number: 291170
The gamma-glutamyltranspeptidase activity of rat uterus and mammary gland was studied in ovariectomized, hypophysectomized and ovariectomized-hypophysectomized rats under different hormonal and drug treatments. The uterine enzyme appears to be mainly dependent on a direct action of estradiol and the mammary gland enzymatic activity is dependent on prolactin. Our result, however, do not exclude a possible role of estradiol in the regulation of prolactin effects on mammary gland enzymatic activity.