Effect of alcohol intoxication on ascorbic and dehydroascorbic acid levels in rat tissue. and human blood
Shugaleĭ, I.S.; Degtiar, V.V.; Butvin, I.N.; Grivenko, G.P.
Ukrainskii Biokhimicheskii Zhurnal 58(3): 81-83
1986
ISSN/ISBN: 0201-8470 PMID: 3727042 Document Number: 282683
It is found that acute ethanol intoxication is accompanied by a decrease in the ascorbic acid content in the brain, liver and kidneys. The content of dehydroascorbic acid in kidneys in this case increases and in the brain tends to decrease. The chronic alcohol intoxication of rats has an opposite (as compared to the acute intoxication) effect on changes in the content of ascorbic and dehydroascorbic acids in the studied organs. People with chronic alcohol intoxication have the lower content of ascorbic acid in blood plasma and the higher content in erythrocytes, the content of dehydroascorbic acid being increased.