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General and local reactions in the proteolytic system during the development of experimental pneumonia

Kubyshkin, A.V.

Biulleten' Eksperimental'noi Biologii i Meditsiny 102(10): 400-402

1986

ISSN/ISBN: 0365-9615
PMID: 3533173
Document Number: 281603
Proteolytic enzymes and their inhibitors were studied in the serum and bronchoalveolar lavage of rats with acute and chronic experimental pulmonary inflammation. An increase in the inhibitory potential of the blood serum and bronchoalveolar lavage at the acute stage of inflammation was shown. At the chronic stage of pulmonary inflammation the level of the main inhibitors decreased to normal or zero values in the blood and lavage fluid, respectively. It was observed that alpha 1-proteinase inhibitor serum concentration correlated with the level of bronchoalveolar antitrypsin.

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