Use of monospecific antibodies for determining the antigenic determinant composition in the hemagglutinins of the H3N2 influenza viruses of 1979-1983
Isaeva, E.I.; Rovnova, I.Z.; Platonova, A.L.; Kosiakov, P.N.
Voprosy Virusologii 31(2): 153-157
1986
ISSN/ISBN: 0507-4088 PMID: 2425492 Document Number: 279600
The study of the antigenic composition of hemagglutinins of influenza H3N2 viruses isolated during epidemic outbreaks in 1979-1983, carried out by means of monospecific antibodies to individual antigenic determinants, showed heterogeneity of the antigenic structure of epidemically active variants. Some variants were antigenically identical to A/Bangkok/1/79 virus. Hemagglutinin structure of A/Shanghai/31/80, A/Philippines/2/82 and the like was found to contain a qualitatively new antigenic determinant heretofore undetectable in H1N1, H3N2 viruses.