A comparison of the effects of fentanyl and alfentanil on the sleeping times of the intravenous induction agents
Dingwall, A.E.; Pleuvry, B.J.
Journal of Pharmacy and Pharmacology 38(4): 323-325
1986
ISSN/ISBN: 0022-3573 PMID: 2872304 Document Number: 277878
The effect of increasing doses of fentanyl and alfentanil administered before four intravenous induction agents (thiopentone, methohexitone, Althesin and etomidate) on the sleeping time were studied in mice. A biphasic pattern of sleeping time was noted with the more rapidly metabolized and eliminated compounds. Possible explanations are discussed.
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