Experimental documentation of presence of purinergic receptors at human atria
Marmo, E.; Filippelli, A.; Iarussi, D.; Matera, C.; Lampa, E.; Acampora, R.; Soreca, S.; Tortora, G.
International Journal of Tissue Reactions 8(5): 411-419
1986
ISSN/ISBN: 0250-0868 PMID: 3781771 Document Number: 276018
Our experimental data suggest the likelihood that there is a purinergic inhibition on human atria; it appears that inhibition is mediated via P1/Ri (A-1/Ri) and P-2 receptors. Adenosine and ATP produced inhibitory effects on chronotropism and inotropism via P1/Ri (A-1/Ri) and P-2 receptors respectively.
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