Calorimetric properties of mixtures of distearoylphosphatidylcholine and sulfatides with definite fatty acid composition
Viani, P.; Marchesini, S.; Cervato, G.; Cestaro, B.
Biochemistry International 12(1): 125-135
1986
ISSN/ISBN: 0158-5231 PMID: 3947371 Document Number: 273633
The thermotropic behavior of multilamellar liposomes prepared from mixtures of distearoyllecithin and sulfatide of definite fatty acid composition, has been studied by DTA calorimetry. The saturated stearoyl- and lignoceroyl-sulfatides do not modify significantly both the .DELTA. H and the Tm of the phase transition of the lecithins. These parameters, on the contrary, are decreased by all the sulfatides containing unsaturated fatty acids. A contrasting effect is at least exhibited by .alpha.-OH-stearoylsulfatide which promotes a decrease in .DELTA. H but not in Tm of the phase transition. The possibility that these sulfatide properties can influence the dynamic interactions and the sovramolecular organization of the phospholipid bilayers has been discussed.