Melanocyte metabolites in the urine of people of different skin colour
Wirestrand, L.E.; Hansson, C.; Rosengren, E.; Rorsman, H.
Acta Dermato-Venereologica 65(4): 345-348
1985
ISSN/ISBN: 0001-5555 PMID: 2413694 Document Number: 265703
The urinary excretion of 2 melanocyte metabolites was studied in normal people of different skin type. The sulphur-free indole derivative 6-hydroxy-5-methoxyindole-2-carboxylic acid was excreted in larger quantities by people with genetically dark skin, whereas the excretion of 5-S-cysteinyldopa was not related to pigment type. No correlation between 5-S-cysteinyldopa and 6-hydroxy-5-methoxyindole-2-carboxylic acid excretion emerged.