Isolation and identification of metabolites of 5-ethyl-2'-deoxyuridine from rat urine
Kaul, R.; Hempel, B.
Arzneimittel-Forschung 35(7): 1055-1057
1985
ISSN/ISBN: 0004-4172 PMID: 4052140 Document Number: 249303
The metabolites of 5-ethyl-2'-deoxyuridine (Aedurid) have been isolated and purified from rat urine by preparative thin-layer and column chromatography. With the aid of 1H-NMR and mass spectroscopy and by comparison with an authentic sample, the major metabolite could be identified as 5-(1-hydroxyethyl)uracil. The minor metabolite was identified as 5-ethyluracil.
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