Preliminary study of the frequency of micronuclei in buccal mucosa cells sampled from patients with laryngeal tumors
Belowska, J.; Fraczek, A.; Rał, Młgorzata.; Schmager, J.; Składzien, J.; Strek, Pł.; Scióg, A.; Trybała, D.
Przeglad Lekarski 61(4): 248-250
2004
ISSN/ISBN: 0033-2240 PMID: 15521576 Document Number: 264528
The examination of frequency of micronuclei was carried out on two groups of patients with tumors of upper respiratory tract: cancer of larynx (36 individuals) and polyps of larynx (13 persons). Groups of habitants from Katowice, Czestochowa and Nowy Sacz (cities with the different level of air pollution) and separately group of smokers, were considered as the control. It was observed that high frequency of micronuclei in cell of buccal mucosa from individuals exposed on mutagenic substances from the air and cigarette smoke could be a marker of higher risk of carcinogenesis.