Clinical review and antibacterial effect of aztreonam in infections in obstetrics and gynecology
Fujimoto, S.; Makinoda, S.; Tanaka, T.; Ichinohe, K.
Japanese Journal of Antibiotics 38(12): 3513-3519
1985
ISSN/ISBN: 0368-2781 PMID: 3841730 Document Number: 263484
Clinical effect in obstetrics and gynecology was studied on aztreonam (AZT), a potent monobactam antibiotic for Gram-negative bacteria. AZT was tested for 7 cases and effective for all of them with quite a high effective rate of 100%. Neither side effect nor abnormal laboratory findings were noted and it sufficiently proves the property of AZT, a totally chemical-synthesized product with lower incidence of allergic reaction. The above results suggest that AZT is useful for obstetrics and gynecologic infections in view of its high stability to beta-lactamase and dehydropeptidase and high potency against Gram-negative bacteria.