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Cardiovascular alterations in severe pregnancy-induced hypertension seen with an intravenously given hydralazine bolus

Cotton, D.B.; Gonik, B.; Dorman, K.F.

Surgery Gynecology and Obstetrics 161(3): 240-244

1985

ISSN/ISBN: 0039-6087
PMID: 4035539
Document Number: 260879
The acute cardiovascular effects of a 10 milligram bolus of hydralazine was found to cause a significant increase in heart rate and cardiac index while decreasing mean arterial pressure and systemic vascular resistance index. A wide spectrum of individual responses was seen in terms of peak effects and duration of effects. The role of hydralazine in patients with severe pregnancy-induced hypertension was discussed and possible alternative therapy is suggested.

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