Aminolysis and hydrolysis of formanilide in water solutions. V. Influence of the substituent in para-position

Bergstrand, B.

Acta Pharmaceutica Suecica 22(1): 1-16

1985


ISSN/ISBN: 0001-6675
PMID: 4024965
Document Number: 251988
The kinetics of the hydrolysis and aminolysis of formanilides with different substituents in the para-position were studied. Essentially the same type of kinetics could be observed in all cases, but the alkaline hydrolysis and the aminolysis (with imidazole as catalyzing amine) of p-NO2-formanilide was found to be anomalously fast compared to the other formanilides.

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