Methods for determination of ionophore-type antibiotic residues in animal tissues
Weiss, G.; MacDonald, A.
Journal - Association of Official Analytical Chemists 68(5): 971-980
1985
ISSN/ISBN: 0004-5756 PMID: 4055647 Document Number: 251024
Methods for the analysis of polyether antibiotics in animal tissues and fluids (including milk) are reviewed. For monensin and nigericin, only methods based on bioautography are available. For lasalocid, liquid chromatography methods based on fluorescence detection have been developed for analysis of blood, milk, liver, skin and fat. A confirmatory method for lasalocid is described; this is based on purification by liquid chromatography followed by silylation and pyrolysis gas chromatography-positive chemical ionization mass spectrometry. A procedure for the measurement of lasalocid in dried milk is also described.