Clinical trials of chemotherapy and chemoimmunotherapy of malignant melanoma with unfavorable prognosis after surgical treatment
Dobrek, Z.
Wiadomosci Lekarskie 38(4): 265-270
1985
ISSN/ISBN: 0043-5147 PMID: 3892918 Document Number: 250896
Patients (30) with prognostically unfavorable factors after surgical treatment for malignant melanoma of the skin were studied. All patients received supplementary combined chemotherapy. The patients were randomized, with 14 receiving additional immunostimulation with zymosan. In the group receiving chemotherapy exclusively the % of recurrences during 12 mo. of therapy was higher than in a control group in which the patients were treated exclusively by surgery. In the group of patients receiving chemotherapy and immunostimulation the proportion of recurrences was significantly lower than in the group treated exclusively by chemotherapy.