Clinical course of a case of epileptic encephalopathy with marked dysphasia: a neuropsychological and electroencephalographic study
Matsumoto, A.; Takeuchi, T.; Kumagai, T.; Miyazaki, S.; Hara, K.; Kunishima, N.; Watanabe, K.
No to Hattatsu 17(6): 491-499
1985
ISSN/ISBN: 0029-0831 PMID: 4084415 Document Number: 250589
A neuropsychological and electroencephalographic study was done in a case of epileptic encephalopathy with marked dysphasia. The main linguistic disturbance was marked decrease of expressive language and impairment of auditory comprehension of colloquial language. The feature of the dysphasia resembled that of "global aphasia". There was a significant correlation between the diffuse sharp and wave bursts in EEG and the degree of dysphasia. However, reduction of paroxysmal discharges preceded improvement of the language disorder. Ictal EEG with atypical absence was recorded, and an all-night EEG showed "electrical status epilepticus during slep (ESES)". It was postulated, from these data, that pathophysiology in this case involved both cortical and subcortial area, and the linguistic symptom was not merely "aphasia" nor "agnosia", but was the result of more diffuse epileptic encephalopathy.