A clinical, électroéncephalographic and biochemical study of epileptic children and adolescents and their relatives
Amadian, M.G.; Grabarova, M.I.; Kozhushko, I.F.
Zhurnal Nevropatologii i Psikhiatrii Imeni S.S. Korsakova 76(3): 420-422
1976
ISSN/ISBN: 0044-4588 PMID: 1266517 Document Number: 109952
The paper deals with the role of hereditary factors in the appearance of epilepsy by the aid of clinical, EEG and biochemical methods. The authors studied 35 children and adolescents with epilepsy and 69 of their relatives. In a EEG study fo the relatives of such patients there were 56% of changed curves, which indicate to an increased readiness of the brain to paroxysmal states. Besides, in the group of relatives where the children had epilepsy of an unknown nature the amount of changed curves was higher than that in the group of relatives where the patients had symptomatical epilepsy (62% and 51%). The biochemical data demonstrated some correlations between the bioelectrical brain activity with an increased amount of isoenzyme and LDH-I in the blood sera of relatives of epileptic patients.