Ophthalmological complications of cryptococcal meningitis
Blackie, J.D.; Danta, G.; Sorrell, T.; Collignon, P.
Clinical and Experimental Neurology 21: 263-270
1985
ISSN/ISBN: 0196-6383 PMID: 3843225 Document Number: 249591
Two patients with cryptococcal meningitis associated with ophthalmological complications are described. One patient developed a cryptococcal fundal lesion which disappeared during chemotherapy. Chronically raised intracranial pressure was associated with a visual field defect. This resolved with repeated lumbar punctures. The second patient developed visual deficits secondary to papilloedema and responded to optic nerve decompression. In both cases CT scanning demonstrated swelling of the optic nerves. In the second patient this regressed after decompression. A review of the variety of the ophthalmological complications of cryptococcal meningitis and their prevalence is presented. The risk of developing severe visual disability is assessed.