Metabolism of antipyrine in man
Pautet, F.; Barret, R.; Daudon, M.; Mathian, B.
Pathologie-Biologie 33(7): 777-780
1985
ISSN/ISBN: 0369-8114 PMID: 3909077 Document Number: 246730
Antipyrine is widely used as a model compound to assess the hepatic metabolism in man. This drug is extensively metabolized by the hepatic microsomal drug-oxidizing system, into three main metabolites and six minor compounds of the phase I. The metabolite fate of this drug is not fully understood. A new metabolite pathway including a ring opening seems possible.
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