N-acetyl-beta-D-glucosaminidase in lymphocytes of patients with diabetes mellitus
Lisiewicz, J.; Moszczyński, P.
Folia Haematologica 112(3): 382-390
1985
ISSN/ISBN: 0323-4347 PMID: 2414166 Document Number: 245755
In 55 patients with diabetes mellitus the significant quantitative increase in numbers of N-acetyl-beta-D-glucosaminidase-positive lymphocytes in the peripheral blood has been examined by cytochemical methods. The enzyme-positive lymphocytes of these patients were characterized by prevalence of extralysosomal localization of the enzyme and a decrease in the numbers of those cells having intact enzyme-positive lysosomes. No association between these alterations and therapy with insulin or oral hypoglycemic drug and overweight could be stated.