Indices of the blood kallikrein-kinin and coagulating systems in hypertension patients during treatment

Zholob, V.M.; Vygovskiĭ, V.P.

Klinicheskaia Meditsina 63(1): 74-78


ISSN/ISBN: 0023-2149
PMID: 3846006
Document Number: 244596
The kallikrein-kinin activation was found in 141 patients with stage I and II essential hypertension, while its coagulographic indices were within normal values. The combined treatment intended to decrease the arterial pressure did not significantly affect the kallikrein-kinin parameters though the fibrinolysis activity somewhat increased. Activation of the kallikrein-kinin blood system in essential hypertension patients both prior and during the treatment testifies to its important role in the compensatory-adaptation mechanisms of the hemodynamic regulation in this disease.

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