Toxicity of an original antiemetic preparation dimetpramid
Orlova, T.M.; Tsarichenko, G.V.; Malochkin, V.V.; Legeza, V.I.; Shagoian, M.G.
Farmakologiia i Toksikologiia 48(6): 74-76
1985
ISSN/ISBN: 0014-8318 PMID: 4085635 Document Number: 243455
A new original drug dimetpramid injected per os into mice and rats exhibits moderate toxicity, exerts a weak irritating action on the mucous membranes. The drug is capable of penetrating via the unaffected skin, producing systemic effects. With all routes of administration the drug may have a moderate inhibitory action on ovarian function and the manifestation of the hypotensive effect.