The effect of malathion dust on certain tissues of male rats fed varying levels of dietary protein
Vaishwanar, I.; Mallik, S.
Indian Journal of Physiology and Pharmacology 28(1): 35-41
1984
ISSN/ISBN: 0019-5499 PMID: 6490128 Document Number: 238596
The effects of malathion, an organophosphorus insectide, on tissue levels of acetylcholinesterase (Ache), phosphomonoesterases and transaminases were studied in presence of different levels of dietary proteins. Adult male albino rats weighing 150-200 g were given 5 10 and 20% protein diets containing 400 mg malathion (dust) 5% conc. was decreased in kidney and lungs, in the low protein groups 5 and 10%, whereas its activity was increased in liver, brain and spleen of animals receiving 5% protein, compared to their respective pair-fed animals. Although the degree of alteration in the enzyme profile is less severe, these changes show that high protein diet has a protective role against pesticide hazards, whereas low protein diet provides less stability to the structural integrity of the tissues.