Clinical studies on sulbactam/cefoperazone in the field of obstetrics and gynecology

Ikushima, Y.; Kobayashi, H.; Matsumoto, S.; Shirakawa, K.

Japanese Journal of Antibiotics 37(11): 2251-2255

1984


ISSN/ISBN: 0368-2781
PMID: 6098719
Document Number: 234563
Sulbactam cefoperazone (SBT/CPZ), a combination drug of SBT and CPZ, was administered to 5 cases with obstetrical and gynecological infections in a daily dose of 2-6 g for 3-5 days. Clinical efficacy was good in 4 cases and poor in 1 case with adnexitis. Bacteriologically, organisms were detected in 2 out of 5 cases, beta-lactamase producing P. aeruginosa was detected in 1 case, but, their bacteriological responses were not clarified. Neither side effect nor abnormal laboratory findings due to this drug were observed. From the results we concluded that SBT/CPZ was an effective and safe antibiotic in the field of obstetrics and gynecology.

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