Dynamics of several indices of carbohydrate and lipid metabolism during the period of readaptation after prolonged restriction of movement
Lobova, T.M.; Potapov, P.P.; Chernyi, A.V.
Kosmicheskaia Biologiia i Aviakosmicheskaia Meditsina 18(4): 55-58
1984
ISSN/ISBN: 0321-5040 PMID: 6482362 Document Number: 234468
Eighty-seven white rats were exposed to prolonged hypokinesia. On 90th hypokinesia day the content of cholesterol, free fatty acids and acetone bodies increased and the content of sugar and triglycerides decreased in blood, the content of glycogen decreased and the content of cholesterol increased in liver and skeletal muscles. On the 15th day after exposure most parameters returned to normal. However, glucose-6-phosphate dehydrogenase in liver and adipose tissue increased and remained elevated till recovery day 60. On the 30th recovery day the changes were similar to those during hypokinesia. On the 90th recovery day the content of triglycerides, cholesterol and acetone bodies in blood grew and the content of triglycerides and glycogen in muscles increased.