Monoclonal antibodies in the pathology of infective agents
Cosentino, S.; Russo, R.; Fatuzzo, F.; Nunnari, A.
Minerva Medica 75(38): 2199-2206
1984
ISSN/ISBN: 0026-4806 PMID: 6438562 Document Number: 231506
Reports in the literature on recent significant research into the production of monoclonal antibodies opposing schizomycetes protozoa and viruses are presented. Such research has provided valuable new information about the epidemiology, aetiopathogenesis and prophylaxis of several infectious diseases. Monoclonal antibodies have in fact been used to identify new antigenic determinants in various microorganisms, to show antigenic differences between species, strains, types and development cycles and to reveal the existence of natural antigenic variants. Finally it is reported that only human monoclonal antibodies can be used in human immunoprophylaxis and therapy.